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rabbit anti human fn1 igg antibody (Cell Signaling Technology Inc)

Name: rabbit anti human fn1 igg antibody
Brand: Cell Signaling Technology Inc
Rating: 97 (222 reviews)

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Cell Signaling Technology Inc rabbit anti human fn1 igg antibody

Prognostic value of LYZ and LILRB4 proteins in DLBCL receiving R-CHOP ( n = 37, 10X) and aNSCLC receiving ICIs ( n = 29, 2X and 10X). A Representative IHCs staining of LYZ in patient 1 (PFS = 1697 days) and patient 2 (PFS = 341 days), LILRB4 in patient 3 (PFS = 64 days) and patient 4 (PFS = 826 days). B Kaplan–Meier survival curves of PFS grouped by the LYZ and LILRB4 expression in DLBCL. C Representative mIF staining of LYZ, LILRB4, and pan Cytokeratin. D Kaplan–Meier survival curves of OS grouped by the LYZ and LILRB4 expression in aNSCLC. E Kaplan–Meier survival curves of PFS grouped by the COL3A1 expression and <t>FN1</t> + macrophages in DLBCL. DLBCL: diffuse large B cell lymphoma; R-CHOP: rituximab, cyclophosphamide, doxorubicin: vincristine, and prednisone; aNSCLC: advanced non-small cell lung cancer; ICIs: immune checkpoint inhibitors; IHC: immunohistochemistry; PFS: progression-free survival; mIF: multiple immunofluorescence; and OS: overall survival

Rabbit Anti Human Fn1 Igg Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 222 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti human fn1 igg antibody/product/Cell Signaling Technology Inc
Average 97 stars, based on 222 article reviews

rabbit anti human fn1 igg antibody - by Bioz Stars, 2026-02

97/100 stars

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1) Product Images from "Spatial transcriptomics reveals prognostically LYZ + fibroblasts and colocalization with FN1 + macrophages in diffuse large B-cell lymphoma"

Article Title: Spatial transcriptomics reveals prognostically LYZ + fibroblasts and colocalization with FN1 + macrophages in diffuse large B-cell lymphoma

Journal: Cancer Immunology, Immunotherapy : CII

doi: 10.1007/s00262-025-03968-7

Figure Legend Snippet: Prognostic value of LYZ and LILRB4 proteins in DLBCL receiving R-CHOP ( n = 37, 10X) and aNSCLC receiving ICIs ( n = 29, 2X and 10X). A Representative IHCs staining of LYZ in patient 1 (PFS = 1697 days) and patient 2 (PFS = 341 days), LILRB4 in patient 3 (PFS = 64 days) and patient 4 (PFS = 826 days). B Kaplan–Meier survival curves of PFS grouped by the LYZ and LILRB4 expression in DLBCL. C Representative mIF staining of LYZ, LILRB4, and pan Cytokeratin. D Kaplan–Meier survival curves of OS grouped by the LYZ and LILRB4 expression in aNSCLC. E Kaplan–Meier survival curves of PFS grouped by the COL3A1 expression and FN1 + macrophages in DLBCL. DLBCL: diffuse large B cell lymphoma; R-CHOP: rituximab, cyclophosphamide, doxorubicin: vincristine, and prednisone; aNSCLC: advanced non-small cell lung cancer; ICIs: immune checkpoint inhibitors; IHC: immunohistochemistry; PFS: progression-free survival; mIF: multiple immunofluorescence; and OS: overall survival

Techniques Used: Staining, Expressing, Immunohistochemistry, Immunofluorescence

Prognostic significance of autoantibodies against COL1A2, COL3A1, and FN1 in patients with DLBCL receiving R-CHOP ( n = 20 and 125) and NSCLC treated with ICIs ( n = 36). A Volcano plot, boxplot, and representative density plots of patients illustrating the distribution of COL1A2 autoantibodies in DLBCL. B Kaplan–Meier curve for PFS based on COL1A2 autoantibody levels in DLBCL. C Kaplan–Meier curves for OS and PFS in NSCLC patients receiving immunotherapy, stratified by COL1A2 and COL3A1 mRNA levels in GSE128989 and autoantibody presence, alongside representative density plots of COL1A2 and COL3A1 autoantibodies. D Comparison of FN1 autoantibody levels between healthy controls and DLBCL, with Kaplan–Meier analysis for PFS based on FN1 autoantibody levels. DLBCL: diffuse large B cell lymphoma; R-CHOP: rituximab, cyclophosphamide, doxorubicin: vincristine, and prednisone; NSCLC: non-small cell lung cancer; ICIs: immune checkpoint inhibitor; OS: overall survival; and PFS: progression-free survival

Figure Legend Snippet: Prognostic significance of autoantibodies against COL1A2, COL3A1, and FN1 in patients with DLBCL receiving R-CHOP ( n = 20 and 125) and NSCLC treated with ICIs ( n = 36). A Volcano plot, boxplot, and representative density plots of patients illustrating the distribution of COL1A2 autoantibodies in DLBCL. B Kaplan–Meier curve for PFS based on COL1A2 autoantibody levels in DLBCL. C Kaplan–Meier curves for OS and PFS in NSCLC patients receiving immunotherapy, stratified by COL1A2 and COL3A1 mRNA levels in GSE128989 and autoantibody presence, alongside representative density plots of COL1A2 and COL3A1 autoantibodies. D Comparison of FN1 autoantibody levels between healthy controls and DLBCL, with Kaplan–Meier analysis for PFS based on FN1 autoantibody levels. DLBCL: diffuse large B cell lymphoma; R-CHOP: rituximab, cyclophosphamide, doxorubicin: vincristine, and prednisone; NSCLC: non-small cell lung cancer; ICIs: immune checkpoint inhibitor; OS: overall survival; and PFS: progression-free survival

Techniques Used: Comparison

Figure Legend Snippet: Reagents and tools table

Techniques Used: Formalin-fixed Paraffin-Embedded, Gene Expression, RNA Sequencing, Sequencing, Biomarker Discovery, Clinical Proteomics, Microarray, Control, Immunohistochemistry, Microscopy, Immunofluorescence, Software

Image Search Results

Journal: Cancer Immunology, Immunotherapy : CII

Article Title: Spatial transcriptomics reveals prognostically LYZ + fibroblasts and colocalization with FN1 + macrophages in diffuse large B-cell lymphoma

doi: 10.1007/s00262-025-03968-7

Figure Lengend Snippet: Prognostic value of LYZ and LILRB4 proteins in DLBCL receiving R-CHOP ( n = 37, 10X) and aNSCLC receiving ICIs ( n = 29, 2X and 10X). A Representative IHCs staining of LYZ in patient 1 (PFS = 1697 days) and patient 2 (PFS = 341 days), LILRB4 in patient 3 (PFS = 64 days) and patient 4 (PFS = 826 days). B Kaplan–Meier survival curves of PFS grouped by the LYZ and LILRB4 expression in DLBCL. C Representative mIF staining of LYZ, LILRB4, and pan Cytokeratin. D Kaplan–Meier survival curves of OS grouped by the LYZ and LILRB4 expression in aNSCLC. E Kaplan–Meier survival curves of PFS grouped by the COL3A1 expression and FN1 + macrophages in DLBCL. DLBCL: diffuse large B cell lymphoma; R-CHOP: rituximab, cyclophosphamide, doxorubicin: vincristine, and prednisone; aNSCLC: advanced non-small cell lung cancer; ICIs: immune checkpoint inhibitors; IHC: immunohistochemistry; PFS: progression-free survival; mIF: multiple immunofluorescence; and OS: overall survival

Article Snippet: Rabbit anti-human FN1 IgG antibody , #26836S , Cell Signaling Technology.

Techniques: Staining, Expressing, Immunohistochemistry, Immunofluorescence

Journal: Cancer Immunology, Immunotherapy : CII

Article Title: Spatial transcriptomics reveals prognostically LYZ + fibroblasts and colocalization with FN1 + macrophages in diffuse large B-cell lymphoma

doi: 10.1007/s00262-025-03968-7

Figure Lengend Snippet: Prognostic significance of autoantibodies against COL1A2, COL3A1, and FN1 in patients with DLBCL receiving R-CHOP ( n = 20 and 125) and NSCLC treated with ICIs ( n = 36). A Volcano plot, boxplot, and representative density plots of patients illustrating the distribution of COL1A2 autoantibodies in DLBCL. B Kaplan–Meier curve for PFS based on COL1A2 autoantibody levels in DLBCL. C Kaplan–Meier curves for OS and PFS in NSCLC patients receiving immunotherapy, stratified by COL1A2 and COL3A1 mRNA levels in GSE128989 and autoantibody presence, alongside representative density plots of COL1A2 and COL3A1 autoantibodies. D Comparison of FN1 autoantibody levels between healthy controls and DLBCL, with Kaplan–Meier analysis for PFS based on FN1 autoantibody levels. DLBCL: diffuse large B cell lymphoma; R-CHOP: rituximab, cyclophosphamide, doxorubicin: vincristine, and prednisone; NSCLC: non-small cell lung cancer; ICIs: immune checkpoint inhibitor; OS: overall survival; and PFS: progression-free survival

Article Snippet: Rabbit anti-human FN1 IgG antibody , #26836S , Cell Signaling Technology.

Techniques: Comparison

Journal: Cancer Immunology, Immunotherapy : CII

Article Title: Spatial transcriptomics reveals prognostically LYZ + fibroblasts and colocalization with FN1 + macrophages in diffuse large B-cell lymphoma

doi: 10.1007/s00262-025-03968-7

Figure Lengend Snippet: Reagents and tools table

Article Snippet: Rabbit anti-human FN1 IgG antibody , #26836S , Cell Signaling Technology.

Techniques: Formalin-fixed Paraffin-Embedded, Gene Expression, RNA Sequencing, Sequencing, Biomarker Discovery, Clinical Proteomics, Microarray, Control, Immunohistochemistry, Microscopy, Immunofluorescence, Software

Journal: The American Journal of Pathology

Article Title: Fibroblast Activation Protein Regulates Lesion Burden and the Fibroinflammatory Response in Apoe -Deficient Mice in a Sexually Dimorphic Manner

doi: 10.1016/j.ajpath.2020.01.004

Figure Lengend Snippet: Antibody Resource List

Article Snippet: Fn1 , Multiplex panel 2 , Primary , Rabbit anti-human Fn1 IgG , Millipore-Sigma (F3648) , 1 μg/mL.

Techniques: Staining, Concentration Assay, Plasmid Preparation, Multiplex Assay

Increase in collagen type I (Col1)–rich and concomitant reduction in fibronectin (Fn1)–rich regions of lesions in female fibroblast activation protein (Fap) –deficient mice. A: 10-μm frozen cross-sections of aortic roots from 26-week–old male and female Apoe−/− and Apoe−/−.Fap−/− mice were stained with antibodies targeted to Lama1 (blue), Col1 (green), and Fn1 (red) or isotype IgG controls (A). Total lesional Col1 (B) and Fn1 (C) content was quantified and graphed. D: Higher magnification of lesions shows that Lama1 localizes only to cap regions (small arrow), whereas Col1 and Fn1 stain separate compartments (large arrow). Inset: IgG isotype controls. Areas of colocalized Col1 and Fn1 regions (E) as well as Fn1-only (F) and Col1-only (G) regions were also graphed. ∗P ≤ 0.05, ∗∗P ≤ 0.01, and ∗∗∗P ≤ 0.001. Scale bars: 200 μm (A); 100 μm (D, main image). Original magnification, ×20 (D, inset)

Journal: The American Journal of Pathology

Article Title: Fibroblast Activation Protein Regulates Lesion Burden and the Fibroinflammatory Response in Apoe -Deficient Mice in a Sexually Dimorphic Manner

doi: 10.1016/j.ajpath.2020.01.004

Figure Lengend Snippet: Increase in collagen type I (Col1)–rich and concomitant reduction in fibronectin (Fn1)–rich regions of lesions in female fibroblast activation protein (Fap) –deficient mice. A: 10-μm frozen cross-sections of aortic roots from 26-week–old male and female Apoe−/− and Apoe−/−.Fap−/− mice were stained with antibodies targeted to Lama1 (blue), Col1 (green), and Fn1 (red) or isotype IgG controls (A). Total lesional Col1 (B) and Fn1 (C) content was quantified and graphed. D: Higher magnification of lesions shows that Lama1 localizes only to cap regions (small arrow), whereas Col1 and Fn1 stain separate compartments (large arrow). Inset: IgG isotype controls. Areas of colocalized Col1 and Fn1 regions (E) as well as Fn1-only (F) and Col1-only (G) regions were also graphed. ∗P ≤ 0.05, ∗∗P ≤ 0.01, and ∗∗∗P ≤ 0.001. Scale bars: 200 μm (A); 100 μm (D, main image). Original magnification, ×20 (D, inset)

Article Snippet: Fn1 , Multiplex panel 2 , Primary , Rabbit anti-human Fn1 IgG , Millipore-Sigma (F3648) , 1 μg/mL.

Techniques: Activation Assay, Staining

Summary of Profiling of Atherosclerotic Lesion Composition

Journal: The American Journal of Pathology

Article Title: Fibroblast Activation Protein Regulates Lesion Burden and the Fibroinflammatory Response in Apoe -Deficient Mice in a Sexually Dimorphic Manner

doi: 10.1016/j.ajpath.2020.01.004

Figure Lengend Snippet: Summary of Profiling of Atherosclerotic Lesion Composition

Article Snippet: Fn1 , Multiplex panel 2 , Primary , Rabbit anti-human Fn1 IgG , Millipore-Sigma (F3648) , 1 μg/mL.

Techniques:

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1) Product Images from "Spatial transcriptomics reveals prognostically LYZ + fibroblasts and colocalization with FN1 + macrophages in diffuse large B-cell lymphoma"

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